Step 03 · EveningRecover + RenewGHK-CuManuka Honey

Recover + Renew

GHK-Cu Firming Serum

Concentrated GHK-Cu with antioxidant-rich manuka honey for overnight support, for a firmer, more vibrant-looking complexion by morning.

★★★★★ 5.0 · 6 verified reviews
$144 59 ml / 2 oz.
  • GHK-Cu at effective concentration for overnight renewal
  • Backed by extensive published GHK-Cu research
  • Works during your skin's natural overnight renewal window
  • The texture change most people notice by week two
Small-batch blended in FloridaGHK-Cu core peptideZero filler ingredients

Reviews

What customers notice after a few weeks on the protocol.

★★★★★

I've been using CKYN for about 2 months and the results are legit. My skin is firmer, brighter, and smoother. Forehead wrinkles are disappearing and dark under-eye circles are 100% gone. The deep moisturizing effect of the lotion and balm has been a game changer for me in the dry mountain climate of Colorado. This is one of those products that will become a staple in my routine for years to come. Results are incredible.

Jared E. · Verified Buyer · Dry skin · 8 weeks
★★★★★

Six weeks in. My skin actually holds moisture now, which after years of Colorado winters I'd sort of given up on. Cheeks are smoother. A friend asked what I was doing differently, which was nice. If I had to pick one I'd keep the tallow balm, but I'm using all three.

Emily E. · Verified Buyer · Dry skin · 6 weeks
★★★★★

My skin reacts to everything so I started with just the lotion for two weeks before adding anything else. No reaction. That alone is unusual for me. Around week 3 the redness had calmed down and my skin looked smooth and less irritated in general. I really like what I'm seeing.

Tracy H. · Verified Buyer · Sensitive skin · 6 weeks
★★★★★

I was using five things before this and I've cut down to these three, which honestly I thought would be a downgrade. It wasn't. By about week five my skin looked brighter and more even, mostly through the cheeks. The morning lotion absorbs fast and doesn't pill under makeup, which was my main worry going in because the last serum I tried was a disaster under foundation. Fewer products, better skin. I'll take it.

Heather K. · Verified Buyer · Combination skin · 5 weeks
★★★★★

The tallow balm is what got my attention. I've been trying to simplify my ingredients for a couple of years and usually you pick between a product that works and a product you feel good about. Somewhere around week seven I noticed my skin wasn't feeling tight by the afternoon anymore. Tone looks more even too.

Kali J. · Verified Buyer · Normal to dry skin · 7 weeks
★★★★★

Wife bought it. I used it. Face looks less tired and the forehead lines aren't as deep. Using it after I shave, and my skin looks clearer by the week. Reordered.

Chad M. · Verified Buyer · Normal skin · 8 weeks

Nighttime is when your skin renews.

Overnight renewal

Supports the look of your skin's overnight renewal with GHK-Cu while you sleep.

Firmer by morning

GHK-Cu is associated with a firmer, more vibrant-looking complexion on waking.

Bright, rested look

Antioxidant-rich manuka honey supports a more vibrant, even-toned, rested-looking appearance by morning.

Fewer ingredients. Higher concentration.

The Firming Serum pairs GHK-Cu with antioxidant-rich manuka honey for overnight support during your skin's renewal window. Every ingredient earns its place.

Cu GHK-Cu · Copper Peptide The foundational active, at effective concentration

Glycyl-L-histidyl-L-lysine copper(II), molecular weight 340.38 Da, first identified in human plasma in 1973. We deliver it back at concentrations designed to produce visibly firmer, smoother, more refined-looking skin overnight.

Peer-reviewed research. Published studies associate GHK-Cu with visibly firmer, smoother-looking skin over 8 weeks, and it outperformed vitamin C and retinoic acid comparators in published firmness assessments.
Pickart et al., PMC 2018 · pmc.ncbi.nlm.nih.gov/articles/PMC6073405/
MH Manuka Honey · Overnight Hydration A humectant for a plump, dewy morning finish

New Zealand-sourced manuka honey with unique methylglyoxal compounds, contributing to a visibly hydrated, supple-looking complexion by morning.

Human appearance study. A 2025 study of 40 women using a manuka-based serum for 8 weeks reported improvements in the appearance of fine lines, dark spots, and dryness.
O'Gorman E., et al. (2025). Cureus 17(3):e81244.

Ingredient statements describe appearance outcomes only and are supported by published research. They are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.

Your skin runs on science.

GHK-Cu is a copper tripeptide found naturally in human plasma. Levels peak in your 20s and decline from there. Extensive published research makes it one of the most studied compounds in cosmetic peptide science.

1973

the year GHK-Cu was first identified in human plasma, by Dr. Loren Pickart

Foundational GHK-Cu research
340 Da

the molecular weight of the GHK-Cu copper tripeptide, studied for topical cosmetic use

Published peptide chemistry
3

amino acids bound to copper in a single peptide: glycine, histidine, and lysine

Gly-His-Lys-Cu

All figures from published, peer-reviewed cosmetic science research. These statements refer to the ingredient GHK-Cu as studied in published literature and are not claims about CKYN products specifically. Individual results vary.

The right concentration, not the highest.

Published concentration-response research indicates GHK-Cu is active at nanomolar levels. CKYN formulates to that data and delivers it through the formula, not to a shelf headline.

Brand / ProductGHK-Cu ConcentrationPrice / ozAssessment
The Ordinary Multi-Peptide + Copper 1% ~1% blend $18/oz Under-concentrated effective GHK-Cu; entry-level positioning
NIOD CAIS 3 (Deciem) 1% dual complex $124/oz Sophisticated chemistry; still above the nanomolar optimum
Skin Biology 3% VIP Serum 3% $71/oz Founder-brand; no published evidence 3% outperforms optimally-concentrated formulas
Vitali 3% GHK-Cu Serum 3% $89/oz Aggressive high-concentration; above the nanomolar optimum in some cell models
CKYN Firming SerumThis product Effective concentration ~$72/oz Calibrated to the studied range for visible overnight results

Competitor data compiled from the CKYN Ingredient Science Brief. Verify current pricing and formulations before publishing comparison claims.

Where it fits in your protocol

Your skin rewards consistency. This is one of three daily application windows.

01

Cleanse for the night

Remove the day. Apply to clean, dry skin before bed.

02

Apply the serum

Press several drops over face and neck. Let it absorb fully.

03

Let it work overnight

The serum supports overnight renewal. Wake to a firmer, more refreshed-looking complexion.

What goes into every bottle. And what stays out.

Backed by Research

GHK-Cu is one of the most studied peptides in peer-reviewed cosmetic science. This is not a trending ingredient.

Intentional Ingredients

No filler ingredients, no added fragrance, no label padding. Every ingredient earns its place, backed by published research.

Cruelty-Free

No animal testing at any stage of development or production.

Small-Batch Blended

Small-batch blended in our Florida facility.

Formulated at Concentration

GHK-Cu at levels designed to produce visible change. Not trace amounts added for label claims.

Biocompatible by Design

Grass-fed tallow mirrors your skin's own lipid structure. GHK-Cu is a peptide your body already recognizes.

Before you decide.

What makes this serum different?

It pairs concentrated GHK-Cu with antioxidant-rich manuka honey that supports your skin's overnight renewal window, for a firmer, more vibrant-looking complexion by morning, rather than a single-active serum.

How does this compare to retinol or vitamin C?

Retinol and vitamin C are effective but come with trade-offs: irritation, sun sensitivity, oxidation. GHK-Cu is naturally biocompatible, is not known to cause photosensitivity, and supports a visibly improved-looking complexion without the adjustment period many actives require. GHK-Cu has been studied alongside retinol and vitamin C in published appearance-of-firmness research.

When will I see results?

Most people notice a hydration and texture difference within the first two weeks. Visible improvements in firmness and fine lines typically appear between weeks four and eight with consistent use.

Can I use it with other actives?

Copper peptides are often used in a separate step from strong acids or vitamin C. If you use those, consider reserving the Firming Serum for night. When in doubt, ask your dermatologist.

Morning prepares. Daytime defends. Nighttime renews.

Each product amplifies the next. The protocol creates compound results that no single product, at any price, can match.

The Complete CKYN Protocol

Your skin absorbs what it can in each application. Three doses a day compounds what a single product cannot. Morning, daytime, and night in one system.

$399
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The three CKYN products together: Perfecting Lotion, Tallow Balm, and Firming Serum
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